According to a study entitled “Elongated Periods of Silence in Fibromyalgia Suggesting Central Sensitization as a Pathogenesis,” published in the journal PLOS One, spinal cord processing dysfunction may be responsible for pain in fibromyalgia (FM) patients. .
Fibromyalgia is represented by widespread chronic pain, among other things, but the root cause responsible for chronic pain in FM is still unclear. A recent study showed that central pain amplification is key to the pathogenesis of fibromyalgia. The pathogenesis of FM, also known as “central sensitization,” is a process characterized by increased pain and treatment. sensory in the spinal cord and brain.
Researchers compared the Cutaneous Silence Period (CSP), a spinal reflex triggered by A-delta skin afferents that are used to assess pain management in the central and peripheral nervous systems between FM patients and normal healthy controls. The number of people analyzed was 24 fibromyalgia patients (diagnosed according to the 1990 American College of Rheumatology classification system) and 24 healthy controls of the same age and sex. The CSP of the abductor pollicis brevis muscle present in the hand between the wrist and the base of the thumb was verified using standard electrodiagnostic equipment, as well as the parameters of the patient where statistical information, tender points,
These results suggest that fibromyalgia in the central nervous system is associated with a dysfunction of pain modulation mechanisms. Furthermore, according to the researchers’ study, there was no correlation between PSC and clinical parameters such as VAS score, K-FIQ score, age and height, raising questions about whether or not PSC is used to assess severity of disease. In fact, the researchers indicate that more research is needed to further evaluate the relationship between PSC parameters and clinical information. In their report, the authors write: “In conclusion, supraspinal control dysfunction may be responsible for pain in FM, providing further evidence that